Doctor’s Best Benfotiamine, Non-GMO, Vegan, Gluten Free, Soy Free, Helps Maintain Blood Sugar Levels, 300 mg, 60 Veggie Caps

Benfotiamine raises the blood level of thiamine pyrophosphate (TPP), the biologically active co-enzyme of thiamine. Thiamine and its co-enzyme, TPP thiamine (vitamin B1) plays an essential part in the metabolism of glucose, through actions of it co-enzyme TPP (thiamine pyrophosphate). TPP is formed by the enzymatically catalyzed addition of two phosphate groups donated by ATP to thiamine. TPP also goes by the name thiamine diphosphate. In the cytoplasm of the cell, glucose, a 6-carbon sugar, is metabolized to pyruvic acid, which is converted into acetyl-CoA, otherwise known as active acetate. Acetyl CoA enters the mitochondrion, where it serves as the starting substrate in the Kreb’s cycle citric acid cycle. The Krebs cycle is the primary source of cellular metabolic energy. TPP, along with other co-enzymes, is essential for the removal of CO2 from pyruvic acid, which in turn is a key step in the conversion of pyruvic acid to acetyl CoA. CO2 removal from pyruvic acid is called oxidative decarboxylation and for this reason, TPP was originally referred to as cocarboxylase. TPP is thus vital to the cell’s energy supply. Benfotiamine helps maintain healthy cells in the presence of blood glucose. Acting as a biochemical super-thiamin, it does this through several different cellular mechanisms, as discussed below. Benfotiamine and glucose metabolism benfotiamine normalizes cellular processes fueled by glucose metabolites. As long as glucose remains at normal levels, excess glucose metabolites do not accumulate within the cell. The bulk of the cell’s glucose supply is converted to pyruvic acid, which serves as substrate for production of acetyl CoA, the primary fuel for the krebs cycle. Of the total amount of metabolic energy (in the form of ATP) released from food, the Krebs cycle generates about 90 percent.

Product Features

  • Belonging to the family of compounds knows as allithiamines
  • Benfotiamine is fat-soluble and more bioavailable and physiologically active than thiamin
  • Helps maintain healthy cells in the presence of blood glucose
  • Vegan
  • Label images may vary

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2 Responses to Doctor’s Best Benfotiamine, Non-GMO, Vegan, Gluten Free, Soy Free, Helps Maintain Blood Sugar Levels, 300 mg, 60 Veggie Caps

  1. Anonymous says:

    Important supplement for neuropathy Benfotiamine is vitamin B1 (thiamine) in the most bioavailable form possible, a fat-soluble version which can be taken orally in large, therapeutic dosages because it will not quickly flush out of the body the way ordinary vitamin B1 does.I bought this particular brand because, frankly, it was the only brand currently offered on Amazon that came in 300 mg capsules, and I wanted to get it right away through Prime. I had suffered trauma to my mandibular nerve in a dental procedure,…

  2. Anonymous says:

    It works. It took a full 60 days to feel the benefits. This works! It really does. We got it for my Granny. She barely has any circulation in her feet due to rheumatoid arthritis. The rheumatoid arthritis has twisted both of her knees so much that her knee caps now face backwards. This contortion has effected the nerves as well as the circulation. The neuropathic pain was just awful. She described her pain as heavy and dead. We were desperate and ordered this. IT WORKS FOR NERVE PAIN.It is important to know that it took my Granny the…